From DNA nanotechnology to biomedical understanding: towards single-molecule spatial omics
Ralf Jungmann is Professor of Experimental Physics at LMU Munich and Max Planck Fellow at the MPI for Biochemistry. He studied physics at Saarland University and received his PhD in 2010 from TU Munich, followed by a postdoctoral fellowship at the Wyss Institute at Harvard University.
Jungmann and his team pioneered DNA-based super-resolution fluorescence microscopy, specifically DNA-PAINT. This technique exploits transient DNA-DNA interactions to achieve high spatial resolution and multiplexed images of cellular structures.
In a recent study, his team demonstrated Ångström-scale fluorescence microscopy and single-protein spatial proteomics in neurons, revealing the modes of action of antibodies in cancer and discovering a previously unknown type of synapse.
Register for the seminar by February 11
