Matthias Lutolf is a professor at the Institute of Bioengineering at the École Polytechnique Fédérale in Lausanne (EPFL) in Switzerland.
He studied materials engineering and obtained his PhD in biomedical engineering from ETH Zurich, followed by postdoctoral research at Stanford University. In 2007, he founded his own laboratory at EPFL, where he subsequently served as Director of the Institute of Bioengineering from 2014 to 2018. In addition to his academic role, Lutolf is the Founding Director of Roche's Institute of Human Biology (IHB), where he heads the Department of Translational Bioengineering.
His research focuses on developing advanced bioengineering strategies to guide the self-organization of stem cells and create more reproducible and physiologically relevant organoids. These next-generation organoid systems are accelerating early drug development and transforming how human biology and disease can be studied in vitro.
Lutolf's work has been featured in leading journals such as Nature and Science, and his innovations have spurred the development of commercial technologies and biotech startups focused on personalized medicine and organoid-based testing.